JWH-018
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Batch Traceable
ISO Certified
Synthetic Cannabinoids
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Price from
$210.00
Product Guarantees
- ✓ Certificate of Analysis (COA) provided with every order
- ✓ Full batch traceability and MSDS documentation
- ✓ Temperature-controlled packaging for sensitive reagents
- ✓ 48-hour sourcing guarantee on custom compounds
Need technical specifications?
Our sourcing team can provide SDS sheets, custom dilutions, and bulk pricing. Response within 24 hours.
Request specs →JWH-018 is a potent synthetic cannabinoid from the naphthoylindole family. Synthesized in the 1990s for academic research, it became widely known as the primary psychoactive ingredient in early “Spice” and “K2” herbal incense blends. [1, 2, 3, 4]
Key Facts & Pharmacology:
- How it works: It acts as a full agonist at the brain’s CB₁ and CB₂ cannabinoid receptors. It has a significantly higher binding affinity and efficacy at these receptors compared to natural THC. [1, 2]
- Effects: It mimics many effects of cannabis (relaxation, altered perception), but because it acts as a full agonist rather than a partial agonist, it carries a much higher risk of overdose and adverse reactions. [1, 2, 3]
- Side effects: Severe reactions include acute anxiety, profound agitation, tachycardia, hypertension, seizures, and in rare cases, psychosis and organ failure. [1, 2, 3]
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We offer bulk pricing, GMP upgrades, and custom synthesis on most compounds. Submit a quote request.